Diagnosis of osteoporosis in men patient
usually made of bone densitometry in the context of symptoms or signs
. Like most men have symptoms of skeletal complaints or
fractures, bone mineral density on a scale less than T 2. 5 will be
according to the diagnosis of osteoporosis. If the patient
symptoms, however, T scores less than 2. 5, using men
Standard database shall be held a the same fracture risk as
T score of less than 2. 5 out of use of female database. Without >> << symptoms or signs, so it is necessary to see that the best definition >> << T score of osteoporosis in men. If consensus is reached
Finally, it is likely that the definition of a scale T >> << will be adjusted downward (
, ie less than 2. 5)
correspond to the risk that is present in Caucasian women with a T account
, 2. 5. All reasonable possible causes of bone loss should be considered
. Regular measurement of calcium, phosphorus, alkaline phosphatase
-and whey proteins, as well as liver, kidney, adrenal, pituitary
and thyroid tests destination. Sex steroid measurements >> << should include total testosterone, estrone, estradiol,
, , and sex hormone-binding globulin. Tests calciotropic axis >> << include PTH, 25-hydroksyvytamyna D, and 1.25-dihydroxy D levels. Specific markers of bone formation (serum bone alkaline phosphatase and >> << osteokaltsynu) and bone resorption (urinary >> << calcium and collagen cross-links N-telopeptydu or Dezoksypirydynolin)
received. Percutaneous biopsy of bone may be useful to find out more >> << finally histomorfometricheskoe and dynamic parameters >> disorders. << Biopsy of bone may also help to rule out possible causes
not obvious, such as occult forms of osteomalacia,
bought osteogenesis imperfecta, mastotsytoz, and malignant neoplasms. If the diagnosis is known, the person receives specific therapeutic measures to combat >> << underlying disease. In those patients, as well as
those who do not know the diagnosis, initial therapeutic considerations >> << similar to the approach used for osteoporosis women. Dietary calcium intake should be 1200-1500 mg, according to >> << NIH and the Food and nutrition guidelines for optimal calcium intake >> << (,
). Vitamin D intake should be adequate lasix. People need to get
400-600 IU / day. This is somewhat higher than the current RDA
vitamin D, but according to new Food and Nutrition
principles of. Adequate exercise will definitely be highly recommended. In
people who suffered compression fractures of the spine or other complications >> <<, exercise should circumstances. Nature
antyhravitatsiyi training and degree of problems
sometimes you may need physiotherapy services. Weight
Learning, which provides additional mechanical stimulus for selected sites >> << may also play a role. Smoking should be prohibited, and excessive alcohol use
reception should be avoided. In general, androgen therapy is available at
persons whose sex glands function normally. Information about specific therapies are limited. These performance
alendronate therapy in men will soon be available. This
reasonable to expect that antiresorptive therapy alendronate
and new bisphosphonates will be shown to be effective. Due to the fact that
bone dynamics seem depressed in men with idiopathic osteoporosis
, an attractive alternative therapeutic approach to this syndrome >> << are using anabolic agents. Low dose intermittent PTH administration
could be due to anabolic effects on
cancellous sites (,,
). These impressive results are promising and
further the development of PTH as a therapeutic tool in
idiopathic osteoporosis in men. Other possible approaches to anabolic
which is even more limited data include fluoride and GH. Patients with serial control measure bone mass as they
useful surrogate indexes of therapeutic efficacy. The use of bone markers
which give information on changes in bone formation and resorption
may also be helpful, as was shown in several large studies >> << scale in postmenopausal women (,
). It is possible that
, reduce markers of bone after antirresorptive therapy in men will
provide the same predictive information on therapeutic results
has been shown in postmenopausal women, but such studies have not
available. .
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